Recent publications (Corresponded):
Cell Systems 2025; Nature Reviews Bioengineering 2024; Nature Chemistry 2024; Cell Chemical Biology 2023;
Welcome to Yiwei Lab
We study the biophysics and mechanobiology of organoids and stem cells. We also developed powerful tools on both organ-level and single cell level to enrich our goal. We are situated in Wuhan optics valley, China, where we are proud to have created a creative, collaborative and open-minded Bioengineering Lab.
News & Updates
Check our new Nature Reviews Bioengineering paper!
Our new Nature Reviews Bioengineering paper summarizes the knowledge about the cell volume and mechanism about cell volume compression. We also outlook the applications involving volumetric compression on cells, which can be applied to organoids, stem cells, synthetic biology, and wearable medical devices.
Check our new Nature Chemistry paper!
Our new Nature Chemistry paper developed a new technology to high-throughput and proteome-widely discover endogenous phase separating proteins and biomolecular condensates. We found 522 newly discovered phase separation proteins, 1212 mechenoresponsive phase separation proteins, and many other signaling transduction phase separation proteins.
Check our new Cell Systems Biology paper!
Our new Cell Systems paper developed a new tumor-adipose assembloid model, which reveals mechaical crostalk between cancer cells and adipocytes, as well as its consequence on cell fate change.